Analyzing IL-2-induced vascular leakage with an irAOP as tool

Analyzing IL-2-induced vascular leakage with an irAOP as tool

Immune-related adverse outcome pathways (irAOPs) are a toxicological tool for the structuring of complex immunological mechanisms. The EU-funded IMI-project imSAVAR analyses the applicability of irAOPs in pre-clinical safety assessment of immunotherapies. Here, we use immunotherapy with interleukin...

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Bibliographic Details
Main Authors: Patricia Gogesch, Samira Ortega Iannazzo, Tamara Zimmermann, Remi Villenave, Katherina Sewald, Zoe Waibler
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:Journal of Immunotoxicology
Subjects:
Endothelial cells
permeability
imSAVAR
immune related adverse outcome pathway
vascular leakage
IL-2-immunotherapy
Online Access:https://www.tandfonline.com/doi/10.1080/1547691X.2024.2369123
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https://www.tandfonline.com/doi/10.1080/1547691X.2024.2369123

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