Mitigating Doxorubicin-Induced Skeletal Muscle Toxicity: A Review of Oxidative Stress Mechanisms and the Therapeutic Role of Exercise

Doxorubicin (DOX) is a highly effective chemotherapy drug used in the treatment of many cancers, including solid tumors, hematological malignancies, and soft tissue sarcomas. Despite its potent antitumor effects, DOX is known to have toxic effects in non-tumorous tissues, such as skeletal muscle. Po...

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Bibliographic Details
Main Authors: Quinten W. Pigg, Dillon R. Harris, Daniela Sayuri Inoue, Mariana Janini Gomes
Format: Article
Language:English
Published: MDPI AG 2025-07-01
Series:Antioxidants
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Online Access:https://www.mdpi.com/2076-3921/14/7/870
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