Incomplete recovery of pneumococcal CD4 T cell immunity after initiation of antiretroviral therapy in HIV-infected malawian adults.

HIV-infected African adults are at a considerably increased risk of life-threatening invasive pneumococcal disease (IPD) which persists despite antiretroviral therapy (ART). Defects in naturally acquired pneumococcal-specific T-cell immunity have been identified in HIV-infected adults. We have there...

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Bibliographic Details
Main Authors: Enoch Sepako, Sarah J Glennie, Kondwani C Jambo, David Mzinza, Oluwadamilola H Iwajomo, Dominic Banda, Joep J van Oosterhout, Neil A Williams, Stephen B Gordon, Robert S Heyderman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0100640
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