PPAR-Gamma Agonist Pioglitazone Reduced CD68+ but Not CD163+ Macrophage Dermal Infiltration in Obese Psoriatic Patients

Background. Macrophages are of great importance in the development of obesity and psoriasis. Signaling via PPAR-γ in certain macrophage populations is associated with M2-like features and anti-inflammatory profile. In this research, we evaluated the anti-inflammatory action of pioglitazone by the im...

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Bibliographic Details
Main Authors: Ya. O. Yemchenko, V. I. Shynkevych, K. Ye Ishcheikin, I. P. Kaidashev
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:PPAR Research
Online Access:http://dx.doi.org/10.1155/2020/4548012
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