Case Report: Hereditary spastic paraplegia associated with monoallelic variant in the motor domain of KIF1A

ObjectivesTo investigate the genetic etiology of a familial case with spastic paraplegia.MethodsNeurological examination, clinical and genetic work-up, including exome sequencing (ES), followed by targeted testing, were performed to determine the underlying etiology of the patients’ phenotype.Result...

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Bibliographic Details
Main Authors: Kathryn Sine, David Brodie-Mends, Wafae Chouhani, Lauren Massingham, Saud Alhusaini
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Human Neuroscience
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Online Access:https://www.frontiersin.org/articles/10.3389/fnhum.2025.1568511/full
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