Decrease in tumor content assessed in biopsies is associated with improved treatment outcome response to pembrolizumab in patients with rare tumors

Decrease in tumor content assessed in biopsies is associated with improved treatment outcome response to pembrolizumab in patients with rare tumors

Background Decreased tumor content (TC) in resection specimens after neoadjuvant therapy is used to predict prognosis. We investigated whether TC assessed in biopsy specimens or the shift in TC from baseline to on-treatment can be used accordingly to predict response in patients with rare tumors who...

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Main Authors: Sinchita Roy-Chowdhuri, Ravi Murthy, Aung Naing, Joud Hajjar, Kenneth R Hess, Coya Tapia, Phyu P. Aung, Mingxuan Xu, Fengying Ouyang, Anas Alshawa, Gopal Singh, Vincent Yang, Lilibeth Castillo, Hung Le, Bettzy Stephen, Ignacio Wistuba
Format: Article
Language:English
Published: BMJ Publishing Group 2020-05-01
Series:Journal for ImmunoTherapy of Cancer
Online Access:https://jitc.bmj.com/content/8/1/e000665.full
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https://jitc.bmj.com/content/8/1/e000665.full

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