Secreted neurofilament light chain after neuronal damage induces myeloid cell activation and neuroinflammation

Secreted neurofilament light chain after neuronal damage induces myeloid cell activation and neuroinflammation

Summary: Neurofilament light chain (NfL) is a neuron-specific cytoskeletal protein that provides structural support for axons and is released into the extracellular space following neuronal injury. While NfL has been extensively studied as a disease biomarker, the underlying release mechanisms and r...

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Bibliographic Details
Main Authors: Olga I. Kahn, Sara L. Dominguez, Caspar Glock, Margaret Hayne, Steve Vito, Arundhati Sengupta Ghosh, Max Adrian, Braydon L. Burgess, William J. Meilandt, Brad A. Friedman, Casper C. Hoogenraad
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:Cell Reports
Subjects:
CP: Neuroscience
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124725001536
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http://www.sciencedirect.com/science/article/pii/S2211124725001536

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