Resynchronization of microglial activity in the brain is associated with restoration of motor function in Parkinson’s disease

Abstract Neuroinflammation is a key factor in Parkinson’s disease (PD) pathogenesis. However, the regional heterogeneity of biomarkers related to inflammation in PD is less well defined. We developed [18F]GSK PET imaging to quantify neuroinflammation via the P2X7 receptor (P2X7R) in A53T PD male mic...

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Bibliographic Details
Main Authors: Peizhen Ye, Lei Bi, Yifan Qiu, Min Yang, Yongshan Liu, Yuyi Hou, Pengcheng Zheng, Xiaojuan Cao, Jing Su, Hongjun Jin
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-025-08602-x
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