Salivary Proteome Insights: Evaluation of Saliva Preparation Methods in Mucopolysaccharidoses Research

Salivary Proteome Insights: Evaluation of Saliva Preparation Methods in Mucopolysaccharidoses Research

<b>Background:</b> This research aimed to compare the traditional in-solution digestion (inSol) and solid-phase-enhanced sample preparation (SP3) methods for salivary proteomics, with a focus on identifying mucopolysaccharidosis (MPS)-relevant proteins. <b>Methods:</b> Saliva...

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Bibliographic Details
Main Authors: Maria-Andreea Soporan, Ioana-Ecaterina Pralea, Maria Iacobescu, Radu Cristian Moldovan, Camelia Alkhzouz, Diana Miclea, Cristina-Adela Iuga
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:Biomedicines
Subjects:
saliva sample preparation
bottom-up proteomics
in-solution digestion
single-pot solid-phase-enhanced sample preparation (SP3)
mucopolysaccharidosis
Online Access:https://www.mdpi.com/2227-9059/13/3/662
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https://www.mdpi.com/2227-9059/13/3/662

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