<i>NALCN</i> Promoter Methylation as a Biomarker for Metastatic Risk in a Cohort of Non-Small Cell Lung Cancer Patients

<i>NALCN</i> Promoter Methylation as a Biomarker for Metastatic Risk in a Cohort of Non-Small Cell Lung Cancer Patients

Liquid biopsy enables real-time monitoring of tumor development and response to therapy through the analysis of CTCs and ctDNA. NALCN is a sodium leak channel that is frequently involved in tumor evolution and immunity and acts as a tumor suppressor. Deletion of NALCN has been shown to increase canc...

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Main Authors: Eleni Thanou, Dora Lontra, Ioanna Balgouranidou, Eleni Efthimiadou, Alexandra Delipetrou, Emilia Tsaroucha, Maria Theodosiou, Vassilis Georgoulias, Athanasios Kotsakis, Evi Lianidou, Athina Markou
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Biomolecules
Subjects:
NALCN
methylation
NSCLC
metastasis
prognostic biomarker
Online Access:https://www.mdpi.com/2218-273X/14/12/1514
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