High molecular weight hyaluronic acid alleviates ovariectomy-induced bone loss in mice

High molecular weight hyaluronic acid alleviates ovariectomy-induced bone loss in mice

Abstract Background The rapid decline in ovarian function associated with menopause promotes osteoclast differentiation and increases bone resorption, disrupting of bone homeostasis and increasing the risk of osteoporosis. Hyaluronic acid (HA) is a polysaccharide ubiquitously present in the connecti...

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Main Authors: Khangarid Tenger, Keiichiro Komori, Ami Maehara, Kyosuke Miyazaki, Eriko Marukawa, Toshitaka Yoshii, Kunikazu Tsuji
Format: Article
Language:English
Published: BMC 2024-12-01
Series:BMC Musculoskeletal Disorders
Subjects:
Hyaluronic acid
Osteoporosis
Ovariectomy
Receptor activator of nuclear factor kappa-B ligand
Online Access:https://doi.org/10.1186/s12891-024-08161-y
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https://doi.org/10.1186/s12891-024-08161-y

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