The Role of Interleukin-23 in the Early Development of Emphysema in HIV1+ Smokers
Rationale. Matrix metalloproteinase-9 (MMP-9) expression is upregulated in alveolar macrophages (AM) of HIV1+ smokers who develop emphysema. Knowing that lung epithelial lining fluid (ELF) of HIV1+ smokers contains increased levels of inflammatory cytokines compared to HIV1− smokers, we hypothesized...
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| Main Authors: | Igor Z. Barjaktarevic, Ronald G. Crystal, Robert J. Kaner |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2016-01-01
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| Series: | Journal of Immunology Research |
| Online Access: | http://dx.doi.org/10.1155/2016/3463104 |
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