The Role of Interleukin-23 in the Early Development of Emphysema in HIV1+ Smokers

Rationale. Matrix metalloproteinase-9 (MMP-9) expression is upregulated in alveolar macrophages (AM) of HIV1+ smokers who develop emphysema. Knowing that lung epithelial lining fluid (ELF) of HIV1+ smokers contains increased levels of inflammatory cytokines compared to HIV1− smokers, we hypothesized...

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Bibliographic Details
Main Authors: Igor Z. Barjaktarevic, Ronald G. Crystal, Robert J. Kaner
Format: Article
Language:English
Published: Wiley 2016-01-01
Series:Journal of Immunology Research
Online Access:http://dx.doi.org/10.1155/2016/3463104
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