Repurposing Bacopa monnieri extracts containing Aquaporin-1 blockers to improve systemic oxidative stress: The BacOxy_I study

Repurposing Bacopa monnieri extracts containing Aquaporin-1 blockers to improve systemic oxidative stress: The BacOxy_I study

Summary: Objectives: To evaluate the efficacy of Bacopa monnieri (BM) containing Bacopaside II, a specific Aquaporin 1 (AQP1)-blocker, on systemic oxidative stress. Background: AQP1, is a peroxiporin which facilitates hydrogen peroxide transmembrane passage. It is predominantly expressed in endothe...

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Main Authors: Hasnae Boughaleb, Roxane Verdoy, Amandine Pochet, Nathalie Fabian, Ramona Bella, Gopinath Muruganandam, Raphaël Frédérick, Karim Zouaoui Boudjeltia, Axelle Bourez, Cédric Delporte, Pierre Van Antwerpen, Annie Robert, Vincent Haufroid, Joseph P. Dewulf, Jean-Luc Balligand, Virginie Montiel
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Advances in Redox Research
Subjects:
Oxidative stress
Reactive oxygen species (ROS)
Endothelial dysfunction
Aquaporin 1 (AQP1)
Bacopaside II
Bacopa monnieri
Online Access:http://www.sciencedirect.com/science/article/pii/S2667137925000074
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