Genomic characterization and antibiotic susceptibility of biofilm-forming Borrelia afzelii and Borrelia garinii from patients with erythema migrans

Genomic characterization and antibiotic susceptibility of biofilm-forming Borrelia afzelii and Borrelia garinii from patients with erythema migrans

BackgroundBorrelia afzelii and Borrelia garinii are the leading causes of Lyme borreliosis (LB) in Europe. Persistent LB forms may involve biofilms, potentially contributing to antibiotic tolerance.MethodsWhole genome sequencing (WGS) was conducted on 7 B. afzelii and 5 B. garinii isolates from eryt...

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Main Authors: Giorgia Fabrizio, Ilaria Cavallo, Francesca Sivori, Mauro Truglio, Daniela Kovacs, Massimo Francalancia, Giovanna D’Agosto, Elisabetta Trento, Grazia Prignano, Arianna Mastrofrancesco, Eva Ruzič-Sabljič, Fulvia Pimpinelli, Enea Gino Di Domenico
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Lyme disease
Borrelia afzelii
skin
erythema migrans
biofilm
Borrelia garinii
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2025.1619660/full
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https://www.frontiersin.org/articles/10.3389/fcimb.2025.1619660/full

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