The USH3A causative gene clarin1 functions in Müller glia to maintain retinal photoreceptors.

Mutations in CLRN1 cause Usher syndrome type IIIA (USH3A), an autosomal recessive disorder characterized by hearing and vision loss, and often accompanied by vestibular dysfunction. The identity of the cell types responsible for the pathology and mechanisms leading to vision loss in USH3A remains el...

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Bibliographic Details
Main Authors: Hannah J T Nonarath, Samantha L Simpson, Tricia L Slobodianuk, Hai Tran, Ross F Collery, Astra Dinculescu, Brian A Link
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-03-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1011205
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