Future perspectives for PDE5 inhibitors bridging the gap between cardiovascular health and psychological status

Future perspectives for PDE5 inhibitors bridging the gap between cardiovascular health and psychological status

Abstract The serendipitous discovery that inhibiting type 5 phosphodiesterase (PDE5) using sildenafil, a potent PDE5 inhibitor (PDE5i) initially developed for cardioprotection, introduced the possibility of orally managing erectile dysfunction (ED) led to an increase in research data, which are curr...

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Bibliographic Details
Main Authors: Andrea Sansone, Eugenia Guida, Susanna Dolci, Valeria Frangione, Amanda Asso, Gilberto Bellia, Emmanuele A. Jannini
Format: Article
Language:English
Published: BMC 2025-01-01
Series:Basic and Clinical Andrology
Subjects:
Cardiovascular disease
Erectile disfunction
Oral Film
PDE5i
Sildenafil
Online Access:https://doi.org/10.1186/s12610-024-00245-y
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https://doi.org/10.1186/s12610-024-00245-y

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