Antiproliferative and Morphological Effects of Fenretinide Lipid Nanosystems in Colon Adenocarcinoma Cells

Antiproliferative and Morphological Effects of Fenretinide Lipid Nanosystems in Colon Adenocarcinoma Cells

<b>Objective:</b> Colon adenocarcinoma is characterized by the downregulation of the retinoic acid receptor, making natural retinoids such as all-trans retinoic acid, 9-cis retinoic acid and 13-cis retinoic acid effective in treatment and chemoprevention due to their ability to increase...

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Main Authors: Lorenzo Anconelli, Francesca Farioli, Pietro Lodeserto, Aikaterini Andreadi, Francesca Borsetti, Manuela Voltattorni, Lucrezia Galassi, Martina Rossi, Giovanna Farruggia, Paolo Blasi, Isabella Orienti
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Pharmaceutics
Subjects:
4-hydroxyphenyl retinamide
all-trans retinoic acid
antitumor activity
quantitative phase imaging microscopy
mitochondrial membrane potential
reactive oxygen species
Online Access:https://www.mdpi.com/1999-4923/16/11/1421
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