Harnessing extracellular vesicles from adipose-derived stem cells for the treatment of 4-vinylcyclohexene diepoxide-induced premature ovarian insufficiency

Harnessing extracellular vesicles from adipose-derived stem cells for the treatment of 4-vinylcyclohexene diepoxide-induced premature ovarian insufficiency

Abstract Background Premature ovarian insufficiency (POI) is a challenging condition with limited effective treatments. Adipose-derived stem cells (ADSCs) have demonstrated potential in tissue repair, and their extracellular vesicles (ADSC-EVs) show more safety in clinical translation. However, the...

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Main Authors: Yanquan Li, Feng Chen, Wei Zhao, Di Sun, Li Zhang, Rui Qiao, Qianhui Hu, Songmao Li, Boyuan Chen, Haixia Ding, Meiling Zhang, Qing Zhang, Fanghao Guo, Wen Li
Format: Article
Language:English
Published: BMC 2025-08-01
Series:Stem Cell Research & Therapy
Subjects:
Premature ovarian insufficiency
4-vinylcyclohexene diepoxide
Adipose-derived stem cells
Extracellular vesicles
Online Access:https://doi.org/10.1186/s13287-025-04553-6
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https://doi.org/10.1186/s13287-025-04553-6

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