TMT-based quantitative proteomics analysis of serum-derived exosomes in patients with juvenile gout

TMT-based quantitative proteomics analysis of serum-derived exosomes in patients with juvenile gout

ObjectivesThe purpose of this study was to compare the proteomics of serum-derived exosomes in juvenile gout (J-Gout), juvenile hyperuricemia (J-HUA) and oligoarticular juvenile idiopathic arthritis (oJIA).MethodsSerum-derived exosomes were isolated from patients using a qEV column combined with the...

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Bibliographic Details
Main Authors: Zhuyi Ji, Shaoling Zheng, Ling Liang, Lixin Huang, Shanmiao Sun, Zhixiang Huang, Yuebing He, Xia Pan, Tianwang Li, Yukai Huang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Endocrinology
Subjects:
juvenile gout
exosomes
TMT
proteomics
biomarker
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2025.1460218/full
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https://www.frontiersin.org/articles/10.3389/fendo.2025.1460218/full

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