RETRACTED: In Vivo Clearance of Apoptotic Debris From Tumor Xenografts Exposed to Chemically Modified Tetrac: Is There a Role for Thyroid Hormone Analogues in Efferocytosis?

RETRACTED: In Vivo Clearance of Apoptotic Debris From Tumor Xenografts Exposed to Chemically Modified Tetrac: Is There a Role for Thyroid Hormone Analogues in Efferocytosis?

Apoptosis is induced in cancer cells and tumor xenografts by the thyroid hormone analogue tetraiodothyroacetic acid (tetrac) or chemically modified forms of tetrac. The effect is initiated at a hormone receptor on the extracellular domain of plasma membrane integrin αvβ3. The tumor response to tetra...

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Bibliographic Details
Main Authors: Kavitha Godugu, Shaker A. Mousa, Gennadi V. Glinsky, Hung-Yun Lin, Paul J. Davis
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-03-01
Series:Frontiers in Endocrinology
Subjects:
chemokine
efferocytosis
integrin αvβ3
phagocytosis
tetraiodothyroacetic acid (tetrac)
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2022.745327/full
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https://www.frontiersin.org/articles/10.3389/fendo.2022.745327/full

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