Transcriptomic Signature of Frailty in Older Patients With Cardiovascular Disease Undergoing Cardiac Surgery or TAVI

Transcriptomic Signature of Frailty in Older Patients With Cardiovascular Disease Undergoing Cardiac Surgery or TAVI

ABSTRACT Background Deterioration of functional capacity mostly determinates frailty in older patients with cardiovascular disease (CVD). Elucidating the pathophysiological mechanisms of physical frailty is an important goal for improving functional health‐related outcomes. Our objective was the det...

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Main Authors: Omar Baritello, Simon H. Sündermann, Kristian Espinosa‐Garnica, Jörg Kempfert, Markus Jähnert, Nick L. Beetz, Dominik Geisel, Jasmin Gaugel, Julia Rominger, Ursula Müller‐Werdan, Catrin Herpich, Kristina Norman, Alexandra Chadt, Hadi Al‐Hasani, Heinz Völler, Annett Salzwedel, Heike Vogel
Format: Article
Language:English
Published: Wiley 2025-06-01
Series:Journal of Cachexia, Sarcopenia and Muscle
Subjects:
cardiovascular disease
frailty
muscle function
older cardiac patients
sarcopenia
transcriptomics
Online Access:https://doi.org/10.1002/jcsm.13846
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https://doi.org/10.1002/jcsm.13846

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