Asgard Arf GTPases can act as membrane-associating molecular switches with the potential to function in organelle biogenesis

Asgard Arf GTPases can act as membrane-associating molecular switches with the potential to function in organelle biogenesis

Abstract Inward membrane budding, i.e., the bending of membrane towards the cytosol, is essential for forming and maintaining eukaryotic organelles. In eukaryotes, Arf GTPases initiate this inward budding. Our research shows that Asgard archaea genomes encode putative Arf proteins (AArfs). AArfs pos...

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Main Authors: Jing Zhu, Ruize Xie, Qiaoying Ren, Jiaming Zhou, Chen Chen, Meng-Xi Xie, You Zhou, Yan Zhang, Ningjing Liu, Jinchao Wang, Zhengwei Zhang, Xipeng Liu, Wupeng Yan, Qingqiu Gong, Liang Dong, Jinwei Zhu, Fengping Wang, Zhiping Xie
Format: Article
Language:English
Published: Nature Portfolio 2025-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-57902-7
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https://doi.org/10.1038/s41467-025-57902-7

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