Electroacupuncture alleviates the relapse of behaviors associated with pain sensory memory and pain-related aversive memory by activating MORs and inhibiting GABAergic neurons in the insular cortex

Electroacupuncture alleviates the relapse of behaviors associated with pain sensory memory and pain-related aversive memory by activating MORs and inhibiting GABAergic neurons in the insular cortex

Pain memory, which includes sensory and emotional memory, is one of the main causes of pain complications and prolongation. Recent research has identified the insular cortex (IC) as a critical brain region involved in the integration of information pertaining to pain, emotion, reward, cognition and...

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Main Authors: Mengdi Xie, Yuxin Hu, Miaoling Ji, Zui Shen, Xiangnan Yao, Haiju Sun, Xixiao Zhu, Yiping Xie, Shuting Zhou, Chi Xu, Xiaofen He, Boyi Liu, Jianqiao Fang, Xiaomei Shao
Format: Article
Language:English
Published: Elsevier 2025-07-01
Series:Brain Research Bulletin
Subjects:
Insular cortex
μ opioid receptor
GABAergic neurons
Pain sensory memory
Pain-related aversive memory
Electroacupuncture
Online Access:http://www.sciencedirect.com/science/article/pii/S0361923025002060
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