Clinical characteristics and therapeutic determinants of <i>RUNX1::RUNX1T1</i> differ from those of <i>CBFB::MYH11</i> acute myeloid leukemia

Clinical characteristics and therapeutic determinants of <i>RUNX1::RUNX1T1</i> differ from those of <i>CBFB::MYH11</i> acute myeloid leukemia

Core binding factor acute myeloid leukemia (CBF-AML) includes RUNX1::RUNX1T1 and CBFB::MYH11 AML. To investigate whether they should be regarded as distinct entities and treated separately, we retrospectively analyzed 536 patients with CBF-AML aged 60 years or younger. For CBFB::MYH11 AML, no outco...

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Main Authors: Miao Yang, Wenting Wang, Guangji Zhang, Shaowei Qiu, Bingcheng Liu, Yingchang Mi, Ying Wang, Jianxiang Wang, Hui Wei
Format: Article
Language:English
Published: Ferrata Storti Foundation 2025-04-01
Series:Haematologica
Online Access:https://haematologica.org/article/view/12048
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https://haematologica.org/article/view/12048

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