PINK1-Interacting Proteins: Proteomic Analysis of Overexpressed PINK1

Recent publications suggest that the Parkinson's disease- (PD-) related PINK1/Parkin pathway promotes elimination of dysfunctional mitochondria by autophagy. We used tandem affinity purification (TAP), SDS-PAGE, and mass spectrometry as a first step towards identification of possible substrates...

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Bibliographic Details
Main Authors: Aleksandar Rakovic, Anne Grünewald, Lisa Voges, Sarah Hofmann, Slobodanka Orolicki, Katja Lohmann, Christine Klein
Format: Article
Language:English
Published: Wiley 2011-01-01
Series:Parkinson's Disease
Online Access:http://dx.doi.org/10.4061/2011/153979
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