Multi-omics study of mitochondrial dysfunction in the pathogenesis of hyperuricemia

Multi-omics study of mitochondrial dysfunction in the pathogenesis of hyperuricemia

Background Mitochondrial dysfunction is linked to hyperuricemia (HUA), but its genetic pathophysiology is not yet fully understood. We employed Mendelian randomization (MR) to integrate multi-omics data and explore the associations between mitochondrial-related genes and HUA.Methods We conducted a s...

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Bibliographic Details
Main Authors: Yuechang Hong, Minghui Yang, Xin Xu, Peng Wang, Minqiang Fu, Renying Xiong, Jianjiang OuYang
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Renal Failure
Subjects:
Hyperuricemia
Mendelian randomization
mitochondrion
methylation
gene expression
protein
Online Access:https://www.tandfonline.com/doi/10.1080/0886022X.2025.2532855
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https://www.tandfonline.com/doi/10.1080/0886022X.2025.2532855

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