The Effect and Treatment of PIK3CA Mutations in Breast Cancer: Current Understanding and Future Directions

Gene mutations in PIK3CA, the catalytic subunit of phosphoinositide 3-kinases, are significantly associated with prognosis in breast cancer. This association suggests that breast cancer patients with PIK3CA mutations should receive PIK3CA mutant-specific treatment. This review aimed to investigate n...

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Bibliographic Details
Main Authors: Young-Bin Cho, Kyoung-Sik Park
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:Medicina
Subjects:
Online Access:https://www.mdpi.com/1648-9144/61/3/518
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