Integrative multi-omics analysis reveals the LncRNA 60967.1–PLCD4–ATRA axis as a key regulator of colorectal cancer progression and immune response

Integrative multi-omics analysis reveals the LncRNA 60967.1–PLCD4–ATRA axis as a key regulator of colorectal cancer progression and immune response

Abstract Colorectal cancer (CRC) is a major global health concern, characterized by high morbidity and mortality rates. CRC progression involves intricate molecular networks that remain incompletely understood. In this study, we conducted an integrative multi-omics analysis of transcriptomic, proteo...

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Main Authors: Yiyi Chen, Ningning Zhao, Lingna Xu, Xiya Jia, Fang Liu, Jian Huang, Xuhua Li, Yunfei Wang, Chuanxi Lai, Yanbin Shen, Fei Wang, Yiming Lv, Xuefeng Huang, Fan Zhang, Hongcang Gu, Sheng Dai
Format: Article
Language:English
Published: BMC 2025-06-01
Series:Molecular Cancer
Subjects:
Colorectal cancer
Multi-omics
LncRNAs
Tumor microenvironment
Immunity
Online Access:https://doi.org/10.1186/s12943-025-02359-x
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https://doi.org/10.1186/s12943-025-02359-x

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