Hypomethylation‐Triggered SERPINE1 (Serpin Family E Member 1) Exacerbates Polycystic Ovary Syndrome with Hyperandrogenism Induced by Circadian Disruption

Hypomethylation‐Triggered SERPINE1 (Serpin Family E Member 1) Exacerbates Polycystic Ovary Syndrome with Hyperandrogenism Induced by Circadian Disruption

ABSTRACT Polycystic ovary syndrome (PCOS), a prevalent cause of female infertility, arises from complex interactions between genetic and environmental factors, with hyperandrogenism serving as a core pathological feature. While growing evidence links circadian disruptions to the development of hyper...

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Bibliographic Details
Main Authors: Xueying Geng, Weiwei Chu, Shang Li, Xiying Zhou, Dongshuang Wang, Junyu Zhai, Yun Sun, Zi‐Jiang Chen, Yanzhi Du
Format: Article
Language:English
Published: Wiley 2025-07-01
Series:MedComm
Subjects:
polycystic ovary syndrome
serpine1 (serpin family e member 1)
DNA methylation
circadian disruption exposure
hyperandrogenism
Online Access:https://doi.org/10.1002/mco2.70270
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https://doi.org/10.1002/mco2.70270

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