Screening of novel β-carotene hydroxylases for the production of β-cryptoxanthin and zeaxanthin and the impact of enzyme localization and crowding on their production in Yarrowia lipolytica

Screening of novel β-carotene hydroxylases for the production of β-cryptoxanthin and zeaxanthin and the impact of enzyme localization and crowding on their production in Yarrowia lipolytica

Abstract Zeaxanthin, a vital dietary carotenoid, is naturally synthesized by plants, microalgae, and certain microorganisms. Large-scale zeaxanthin production can be achieved through plant extraction, chemical synthesis, or microbial fermentation. The environmental and health implications of the fir...

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Main Authors: Mladen Soldat, Tadej Markuš, Vasilka Magdevska, Martin Kavšček, Aleksander Johannes Kruis, Jaka Horvat, Gregor Kosec, Štefan Fujs, Uroš Petrovič
Format: Article
Language:English
Published: BMC 2024-11-01
Series:Microbial Cell Factories
Subjects:
Carotenoids
Zeaxanthin
β-cryptoxanthin
Yarrowia lipolytica
Metabolic engineering
Subcellular compartments
Online Access:https://doi.org/10.1186/s12934-024-02569-w
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https://doi.org/10.1186/s12934-024-02569-w

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