The bidirectional regulatory network between ATF4 and lncRNAs in systemic diseases

Long non-coding RNAs (lncRNAs) are pivotal regulators of gene expression across multiple biological contexts, including stress responses and cellular adaptation. Activating transcription factor 4 (ATF4) is a key transcriptional effector of the integrated stress response (ISR), modulating genes invol...

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Bibliographic Details
Main Authors: Dongdong Wu, Mei Huang, Changning Ma, Xuetong Xu, Tianhui Wu, Miao Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Oncology
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Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2025.1562861/full
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