The effects of local and systemic metronidazole on bone healing in mandibular defects: a rat model

Abstract Objective This study evaluated the effects of local and systemic Metronidazole (MTZ) on bone healing in infected mandibular defects using a rat model. Study design Thirty Wistar rats were divided into Control, Local MTZ (L-MTZ), and Systemic MTZ (S-MTZ) groups. Mandibular defects were treat...

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Bibliographic Details
Main Authors: Aysan Lektemur Alpan, Alper Kızıldağ, Özlem Özmen, Necati Zavrak, Zeynep Özdoğan, Aysun Akpınar
Format: Article
Language:English
Published: BMC 2025-07-01
Series:BMC Oral Health
Subjects:
Online Access:https://doi.org/10.1186/s12903-025-06254-1
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