Uncovering Gender and Age Neutrality in CT Values for E and RdRp Gene Amplification in SARS-CoV-2
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic poses a danger to public health across the world. Specific and sensitive testing is vital to tracking and containing the infected individuals. This study examines the characteristics of 705 patients based on gender and age gro...
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Language: | English |
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QAASPA Publisher
2023-12-01
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Series: | BioMed Target Journal |
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Online Access: | https://qaaspa.com/index.php/bmtj/article/view/14 |
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author | Ibrahim A. Naqid Masood Ahmed Hameed Nawfal R. Hussein Shivan Hassan Yousif |
author_facet | Ibrahim A. Naqid Masood Ahmed Hameed Nawfal R. Hussein Shivan Hassan Yousif |
author_sort | Ibrahim A. Naqid |
collection | DOAJ |
description | The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic poses a danger to public health across the world. Specific and sensitive testing is vital to tracking and containing the infected individuals. This study examines the characteristics of 705 patients based on gender and age groups, with a focus on their CT (Cycle Threshold) values associated with E- and RdRp gene amplification. Among the patient cohort, 58.87% were male, while 41.13% were female. Notably, all males and females tested positive for the E gene, achieving a 100% detection rate, whereas the RdRp gene exhibited a slightly lower positive rate of 93.4% in males and 89.6% in females. Statistical analysis through the chi-square test revealed no significant disparities between target genes and gender. Additionally, a one-way ANOVA test demonstrated no significant distinctions between target genes and age groups. This study's findings suggest that gender and age do not significantly influence CT values for E and RdRp gene amplification, and there is no preferred gene for detection, providing valuable insights into the molecular characteristics of the studied cohort. |
format | Article |
id | doaj-art-3618a423380b4e609d8decccad0dd2d1 |
institution | Kabale University |
issn | 2960-1428 |
language | English |
publishDate | 2023-12-01 |
publisher | QAASPA Publisher |
record_format | Article |
series | BioMed Target Journal |
spelling | doaj-art-3618a423380b4e609d8decccad0dd2d12025-01-10T21:54:26ZengQAASPA PublisherBioMed Target Journal2960-14282023-12-0112364010.59786/bmtj.12514Uncovering Gender and Age Neutrality in CT Values for E and RdRp Gene Amplification in SARS-CoV-2Ibrahim A. Naqid0https://orcid.org/0000-0002-7223-2690Masood Ahmed Hameed1https://orcid.org/0009-0004-3883-3590Nawfal R. Hussein2https://orcid.org/0000-0002-7813-9198Shivan Hassan Yousif3https://orcid.org/0009-0001-3916-1640Department of Biomedical Sciences, College of Medicine, University of Zakho, Zakho, 42002, IraqDepartment of Biomedical Sciences, College of Medicine, University of Zakho, Zakho, 42002, IraqDepartment of Biomedical Sciences, College of Medicine, University of Zakho, Zakho, 42002, IraqDepartment of Biomedical Sciences, College of Medicine, University of Zakho, Zakho, 42002, IraqThe severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic poses a danger to public health across the world. Specific and sensitive testing is vital to tracking and containing the infected individuals. This study examines the characteristics of 705 patients based on gender and age groups, with a focus on their CT (Cycle Threshold) values associated with E- and RdRp gene amplification. Among the patient cohort, 58.87% were male, while 41.13% were female. Notably, all males and females tested positive for the E gene, achieving a 100% detection rate, whereas the RdRp gene exhibited a slightly lower positive rate of 93.4% in males and 89.6% in females. Statistical analysis through the chi-square test revealed no significant disparities between target genes and gender. Additionally, a one-way ANOVA test demonstrated no significant distinctions between target genes and age groups. This study's findings suggest that gender and age do not significantly influence CT values for E and RdRp gene amplification, and there is no preferred gene for detection, providing valuable insights into the molecular characteristics of the studied cohort.https://qaaspa.com/index.php/bmtj/article/view/14covid-19sars-cov-2rdrp genee genert-pcr |
spellingShingle | Ibrahim A. Naqid Masood Ahmed Hameed Nawfal R. Hussein Shivan Hassan Yousif Uncovering Gender and Age Neutrality in CT Values for E and RdRp Gene Amplification in SARS-CoV-2 BioMed Target Journal covid-19 sars-cov-2 rdrp gene e gene rt-pcr |
title | Uncovering Gender and Age Neutrality in CT Values for E and RdRp Gene Amplification in SARS-CoV-2 |
title_full | Uncovering Gender and Age Neutrality in CT Values for E and RdRp Gene Amplification in SARS-CoV-2 |
title_fullStr | Uncovering Gender and Age Neutrality in CT Values for E and RdRp Gene Amplification in SARS-CoV-2 |
title_full_unstemmed | Uncovering Gender and Age Neutrality in CT Values for E and RdRp Gene Amplification in SARS-CoV-2 |
title_short | Uncovering Gender and Age Neutrality in CT Values for E and RdRp Gene Amplification in SARS-CoV-2 |
title_sort | uncovering gender and age neutrality in ct values for e and rdrp gene amplification in sars cov 2 |
topic | covid-19 sars-cov-2 rdrp gene e gene rt-pcr |
url | https://qaaspa.com/index.php/bmtj/article/view/14 |
work_keys_str_mv | AT ibrahimanaqid uncoveringgenderandageneutralityinctvaluesforeandrdrpgeneamplificationinsarscov2 AT masoodahmedhameed uncoveringgenderandageneutralityinctvaluesforeandrdrpgeneamplificationinsarscov2 AT nawfalrhussein uncoveringgenderandageneutralityinctvaluesforeandrdrpgeneamplificationinsarscov2 AT shivanhassanyousif uncoveringgenderandageneutralityinctvaluesforeandrdrpgeneamplificationinsarscov2 |