Uncovering Gender and Age Neutrality in CT Values for E and RdRp Gene Amplification in SARS-CoV-2

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic poses a danger to public health across the world. Specific and sensitive testing is vital to tracking and containing the infected individuals. This study examines the characteristics of 705 patients based on gender and age gro...

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Main Authors: Ibrahim A. Naqid, Masood Ahmed Hameed, Nawfal R. Hussein, Shivan Hassan Yousif
Format: Article
Language:English
Published: QAASPA Publisher 2023-12-01
Series:BioMed Target Journal
Subjects:
Online Access:https://qaaspa.com/index.php/bmtj/article/view/14
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author Ibrahim A. Naqid
Masood Ahmed Hameed
Nawfal R. Hussein
Shivan Hassan Yousif
author_facet Ibrahim A. Naqid
Masood Ahmed Hameed
Nawfal R. Hussein
Shivan Hassan Yousif
author_sort Ibrahim A. Naqid
collection DOAJ
description The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic poses a danger to public health across the world. Specific and sensitive testing is vital to tracking and containing the infected individuals. This study examines the characteristics of 705 patients based on gender and age groups, with a focus on their CT (Cycle Threshold) values associated with E- and RdRp gene amplification. Among the patient cohort, 58.87% were male, while 41.13% were female. Notably, all males and females tested positive for the E gene, achieving a 100% detection rate, whereas the RdRp gene exhibited a slightly lower positive rate of 93.4% in males and 89.6% in females. Statistical analysis through the chi-square test revealed no significant disparities between target genes and gender. Additionally, a one-way ANOVA test demonstrated no significant distinctions between target genes and age groups. This study's findings suggest that gender and age do not significantly influence CT values for E and RdRp gene amplification, and there is no preferred gene for detection, providing valuable insights into the molecular characteristics of the studied cohort.
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issn 2960-1428
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publishDate 2023-12-01
publisher QAASPA Publisher
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series BioMed Target Journal
spelling doaj-art-3618a423380b4e609d8decccad0dd2d12025-01-10T21:54:26ZengQAASPA PublisherBioMed Target Journal2960-14282023-12-0112364010.59786/bmtj.12514Uncovering Gender and Age Neutrality in CT Values for E and RdRp Gene Amplification in SARS-CoV-2Ibrahim A. Naqid0https://orcid.org/0000-0002-7223-2690Masood Ahmed Hameed1https://orcid.org/0009-0004-3883-3590Nawfal R. Hussein2https://orcid.org/0000-0002-7813-9198Shivan Hassan Yousif3https://orcid.org/0009-0001-3916-1640Department of Biomedical Sciences, College of Medicine, University of Zakho, Zakho, 42002, IraqDepartment of Biomedical Sciences, College of Medicine, University of Zakho, Zakho, 42002, IraqDepartment of Biomedical Sciences, College of Medicine, University of Zakho, Zakho, 42002, IraqDepartment of Biomedical Sciences, College of Medicine, University of Zakho, Zakho, 42002, IraqThe severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic poses a danger to public health across the world. Specific and sensitive testing is vital to tracking and containing the infected individuals. This study examines the characteristics of 705 patients based on gender and age groups, with a focus on their CT (Cycle Threshold) values associated with E- and RdRp gene amplification. Among the patient cohort, 58.87% were male, while 41.13% were female. Notably, all males and females tested positive for the E gene, achieving a 100% detection rate, whereas the RdRp gene exhibited a slightly lower positive rate of 93.4% in males and 89.6% in females. Statistical analysis through the chi-square test revealed no significant disparities between target genes and gender. Additionally, a one-way ANOVA test demonstrated no significant distinctions between target genes and age groups. This study's findings suggest that gender and age do not significantly influence CT values for E and RdRp gene amplification, and there is no preferred gene for detection, providing valuable insights into the molecular characteristics of the studied cohort.https://qaaspa.com/index.php/bmtj/article/view/14covid-19sars-cov-2rdrp genee genert-pcr
spellingShingle Ibrahim A. Naqid
Masood Ahmed Hameed
Nawfal R. Hussein
Shivan Hassan Yousif
Uncovering Gender and Age Neutrality in CT Values for E and RdRp Gene Amplification in SARS-CoV-2
BioMed Target Journal
covid-19
sars-cov-2
rdrp gene
e gene
rt-pcr
title Uncovering Gender and Age Neutrality in CT Values for E and RdRp Gene Amplification in SARS-CoV-2
title_full Uncovering Gender and Age Neutrality in CT Values for E and RdRp Gene Amplification in SARS-CoV-2
title_fullStr Uncovering Gender and Age Neutrality in CT Values for E and RdRp Gene Amplification in SARS-CoV-2
title_full_unstemmed Uncovering Gender and Age Neutrality in CT Values for E and RdRp Gene Amplification in SARS-CoV-2
title_short Uncovering Gender and Age Neutrality in CT Values for E and RdRp Gene Amplification in SARS-CoV-2
title_sort uncovering gender and age neutrality in ct values for e and rdrp gene amplification in sars cov 2
topic covid-19
sars-cov-2
rdrp gene
e gene
rt-pcr
url https://qaaspa.com/index.php/bmtj/article/view/14
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