Maladaptive Peripheral Ketogenesis in Schwann Cells Mediated by CB1R Contributes to Diabetic Neuropathy

Maladaptive Peripheral Ketogenesis in Schwann Cells Mediated by CB1R Contributes to Diabetic Neuropathy

Abstract Diabetic peripheral neuropathy (DPN) is the most common complication of diabetes. Although studies have previously investigated metabolic disruptions in the peripheral nervous system (PNS), the exact metabolic mechanisms underlying DPN remain largely unknown. Herein, a specific form of meta...

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Bibliographic Details
Main Authors: Weizhen Li, Tuo Yang, Ningning Wang, Baolong Li, Chuikai Meng, Kaiming Yu, Xiongyao Zhou, Rangjuan Cao, Shusen Cui
Format: Article
Language:English
Published: Wiley 2025-04-01
Series:Advanced Science
Subjects:
cannabinoid type 1 receptor
diabetic peripheral neuropathy
ketogenesis
metabolic reprogramming
schwann cell
Online Access:https://doi.org/10.1002/advs.202414547
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https://doi.org/10.1002/advs.202414547

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