Effect of Tofacitinib on Hemostasis in Patients with Ulcerative Colitis: A Comparative Ex Vivo Study

Effect of Tofacitinib on Hemostasis in Patients with Ulcerative Colitis: A Comparative Ex Vivo Study

<b>Background:</b> Tofacitinib is effective for refractory ulcerative colitis (UC), a chronic inflammatory disease of the colonic mucosa. However, its use has been associated with an increased risk of thromboembolic events, prompting regulatory restrictions. Understanding the pathophysio...

Full description

Saved in:
Bibliographic Details
Main Authors: Cristina Sánchez-Sánchez, Fabio Suarez-Trujillo, Cristina Ramírez, Irene Soleto, Jorge Mercado, Macarena Orejudo, Paula J. Martínez, Celia Rubio Collado, Mar Orts, María Jesús Rubio Franco, Antonio Planas, Natalia Acedo, Nora Butta, María Chaparro, Javier P. Gisbert, Montse Baldán-Martín
Format: Article
Language:English
Published: MDPI AG 2025-04-01
Series:Pharmaceuticals
Subjects:
tofacitinib
ulcerative colitis
platelet aggregation
platelet activation
thromboelastometry
Online Access:https://www.mdpi.com/1424-8247/18/4/557
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://www.mdpi.com/1424-8247/18/4/557

Similar Items