miR-146b/Btg2 axis as a potential inducer of islet beta-cell decline during the progression of obesity to T2DM

We evaluated the potential mechanisms responsible for inducing beta-cell decline during the progression of obesity to type 2 diabetes mellitus (T2DM). Between February 2021 and February 2022, 25 subjects with non-diabetic obesity, 20 subjects with obesity and new-onset T2DM, and 25 healthy volunteer...

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Bibliographic Details
Main Authors: Weixuan Wang, Dan Ma, Yong Chen, Rui Cheng, Ting Zhang, Qian Ge, Xi Li
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2025-09-01
Series:Genes and Diseases
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Online Access:http://www.sciencedirect.com/science/article/pii/S2352304225001102
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