Binding of CIB1 to the αIIb tail of αIIbβ3 is required for FAK recruitment and activation in platelets.
<h4>Background</h4>It is believed that activation of c-Src bound to the integrin β3 subunit initiates outside-in signaling. The involvement of αIIb in outside-in signaling is poorly understood.<h4>Objectives</h4>We have previously shown that CIB1 specifically interacts with t...
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| Main Authors: | Meghna U Naik, Tejal U Naik, Ross Summer, Ulhas P Naik |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2017-01-01
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| Series: | PLoS ONE |
| Online Access: | https://doi.org/10.1371/journal.pone.0176602 |
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