Binding of CIB1 to the αIIb tail of αIIbβ3 is required for FAK recruitment and activation in platelets.

<h4>Background</h4>It is believed that activation of c-Src bound to the integrin β3 subunit initiates outside-in signaling. The involvement of αIIb in outside-in signaling is poorly understood.<h4>Objectives</h4>We have previously shown that CIB1 specifically interacts with t...

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Bibliographic Details
Main Authors: Meghna U Naik, Tejal U Naik, Ross Summer, Ulhas P Naik
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0176602
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