Cellular neuroprotection as a modern treatment approach for optic neuropathy

Cellular neuroprotection as a modern treatment approach for optic neuropathy

Aim. To develop technology to create 3D-spheroid multipotent mesenchymal stem cells (MMSC) of limbal cadaveric human eyes, capable of safe and long-term secretion of nerve growth factor (NGF) and brain-derived neurotrophic factor (BDNF).Materials and methods. MMSC were obtained by cultivation of lim...

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Main Authors: S. A. Borzenok, M. Kh. Khubetsova, I. N. Saburina, N. A. Gavrilova, Kh. D. Tonaeva, D. S. Ostrovskiy, N. I. Lanevskaya, N. V. Kosheleva, I. M. Zurina
Format: Article
Language:Russian
Published: Federal Research Center of Transplantology and Artificial Organs named after V.I.Shumakov 2017-04-01
Series:Вестник трансплантологии и искусственных органов
Subjects:
optic neuropathy
limbal multipotent mesenchymal stem cells
3d-culture
cellular spheroids
nerve growth factor (ngf)
brain-derived neurotrophic factor (bdnf)
cell therapy
neuroprotection
Online Access:https://journal.transpl.ru/vtio/article/view/735
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