Ticagrelor versus clopidogrel in CYP2C19 loss-of-function carriers with stroke or TIA stratified by age and renal function: CHANCE-2 trial substudy

Ticagrelor versus clopidogrel in CYP2C19 loss-of-function carriers with stroke or TIA stratified by age and renal function: CHANCE-2 trial substudy

Objective To compare the efficacy and safety of ticagrelor versus clopidogrel in stroke patients who were CYP2C19 loss-of-function (LOF) carriers stratified by age and renal function.Methods Patients in the CHANCE-2 trial were randomized to ticagrelor-aspirin or clopidogrel–aspirin treatment. The pr...

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Bibliographic Details
Main Authors: Yu Wu, Yilun Zhou, Yuesong Pan, Aoming Jin, Xia Meng, Hao Li, Yilong Wang, Yong Jiang, Yongjun Wang
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Renal Failure
Subjects:
Ticagrelor
clopidogrel
stroke
age
renal function
Online Access:https://www.tandfonline.com/doi/10.1080/0886022X.2025.2526684
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https://www.tandfonline.com/doi/10.1080/0886022X.2025.2526684

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