R-loops: a key driver of inflammatory responses in cancer

Abstract R-loops, which are noncanonical three-stranded nucleic acid structures formed when RNA hybridizes with complementary DNA strand while displacing the other DNA strand, have emerged as crucial players in cellular homeostasis and cancer pathogenesis. Here we explore the intricate relationship...

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Bibliographic Details
Main Authors: Seo Yun Lee, Min Jae Kwak, Jae Jin Kim
Format: Article
Language:English
Published: Nature Publishing Group 2025-07-01
Series:Experimental and Molecular Medicine
Online Access:https://doi.org/10.1038/s12276-025-01495-0
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