Clinical and prognostic characteristics of <I>BRCA1/2</I>-associated breast cancer depending on the type of mutation: estrogen signaling pathway and secondary tumors

Clinical and prognostic characteristics of <I>BRCA1/2</I>-associated breast cancer depending on the type of mutation: estrogen signaling pathway and secondary tumors

Background. Currently, there is growth evidence on prognostic and clinical differences in breast cancer (BC) associated with different types of BRCA1 / 2 mutations. At the same time, a triple negative tumor phenotype is not an absolute pathognomonic sign of BRCA1 / 2-associated cancer, where luminal...

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Bibliographic Details
Main Authors: A. I. Stukan, A. Yu. Goryainova, R. A. Murashko, Z. K. Khachmamuk, O. Yu. Chukhray, S. D. Maksimenko, O. A. Goncharova, E. N. Imyanitov, V. A. Porkhanov
Format: Article
Language:Russian
Published: ABV-press 2022-09-01
Series:Опухоли женской репродуктивной системы
Subjects:
breast cancer
brca1 / 2-mutations
polymerase chain reaction
next generation sequencing
multiple tumors
luminal phenotype
triple negative phenotype
Online Access:https://ojrs.abvpress.ru/ojrs/article/view/968
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