Molecular analysis of BRCA1 and BRCA2 genes in La Rioja (Spain): five new variants

Molecular analysis of BRCA1 and BRCA2 genes in La Rioja (Spain): five new variants

Abstract Background To study BRCA1/2 gene variants in La Rioja in the northcentral area of Spain. Methods We performed a molecular analysis of BRCA1 and BRCA2 in 642 individuals from 427 different families from June 2008 to December 2019. Results We identified 71 families with pathogenic variants in...

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Main Authors: Raquel Salazar Saez, Miriam Zorrilla, Rosa Sánchez, Ana Cebollero, Isabel Manrique, Alfonso Martín, Leticia de Ávila, Alejandra Lacalle-Emborujo, Samuel Martin-Rodriguez, Iván Bernardo-González, Martina Alonso
Format: Article
Language:English
Published: BMC 2024-10-01
Series:Hereditary Cancer in Clinical Practice
Subjects:
BRCA1
BRCA2
Breast and ovarian cancer
Hereditary cancer
Pathogenic variants
La Rioja population
Online Access:https://doi.org/10.1186/s13053-024-00296-2
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https://doi.org/10.1186/s13053-024-00296-2

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