Impact of Notch3 Activation on Aortic Aneurysm Development in Marfan Syndrome
Background. The leading cause of mortality in patients with Marfan syndrome (MFS) is thoracic aortic aneurysm and dissection. Notch signaling is essential for vessel morphogenesis and function. However, the role of Notch signaling in aortic pathology and aortic smooth muscle cell (SMC) differentiati...
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Main Authors: | , , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Wiley
2022-01-01
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Series: | Journal of Immunology Research |
Online Access: | http://dx.doi.org/10.1155/2022/7538649 |
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