Longitudinal phenotypic and genomic evidence revealing increased risk of drug resistance accumulation in tuberculosis patients in the counties of central China

Longitudinal phenotypic and genomic evidence revealing increased risk of drug resistance accumulation in tuberculosis patients in the counties of central China

ABSTRACT Drug-resistant tuberculosis (DR-TB) disproportionately affects rural China, yet the molecular and epidemiological drivers of this disparity remain inadequately explored. This study investigates resistance evolution and transmission dynamics in Xianning, China, using longitudinal data from 3...

Full description

Saved in:
Bibliographic Details
Main Authors: Fu-Lin Wang, Rong Chen, Qiao Xu, Xiao-Qin Wang, Feng-Xi Tao, Zi-Kang Huang, You-Tong Zhang, Shu-Qiong Chen, Xue-Jing Wu, Hong-Yuan Cao, Qi Jiang
Format: Article
Language:English
Published: American Society for Microbiology 2025-08-01
Series:Microbiology Spectrum
Subjects:
tuberculosis
drug resistance
whole-genome sequencing
transmission cluster
evolution
resistance mutation
Online Access:https://journals.asm.org/doi/10.1128/spectrum.00380-25
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://journals.asm.org/doi/10.1128/spectrum.00380-25

Similar Items