Modeling mesenchymal stromal cell support to hematopoiesis within a novel 3D artificial marrow organoid system

Modeling mesenchymal stromal cell support to hematopoiesis within a novel 3D artificial marrow organoid system

Abstract The human bone marrow (BM) microenvironment involves hematopoietic and non-hematopoietic cell subsets organized in a complex architecture. Tremendous efforts have been made to model it in order to analyze normal or pathological hematopoiesis and its stromal counterpart. Herein, we report an...

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Main Authors: Bérénice Schell, Lin-Pierre Zhao, Inés M’Sibih, Maria Kalogeraki, Camille Kergaravat, Emilie Lereclus, Pierre Fenaux, Lionel Adès, Antoine Toubert, Marion Espéli, Karl Balabanian, Emmanuel Clave, Nicolas Dulphy, Valeria Bisio
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-025-07717-9
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https://doi.org/10.1038/s41598-025-07717-9

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