Loss of Kat2b impairs intraflagellar transport and the Hedgehog signaling pathway in primary cilia

Loss of Kat2b impairs intraflagellar transport and the Hedgehog signaling pathway in primary cilia

Abstract Primary cilia are sensory organelles that regulate various signaling pathways. When microtubules are compared to a highway, motor proteins carry and transport cargo proteins, which are tuned by post-translational modifications, such as acetylation. However, the role of acetylation in primar...

Full description

Saved in:
Bibliographic Details
Main Authors: Jae Hee Jun, Hwayeon Cha, Je Yeong Ko, Ho-Shik Kim, Kyung Hyun Yoo, Jong Hoon Park
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Scientific Reports
Subjects:
Acetylation
Ciliogenesis
Intraflagellar transport
Kat2b
Primary cilia
Online Access:https://doi.org/10.1038/s41598-025-86292-5
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doi.org/10.1038/s41598-025-86292-5

Similar Items