H3.3 deposition counteracts the replication-dependent enrichment of H3.1 at chromocenters in embryonic stem cells

Abstract Chromocenters in mouse cells are membrane-less nuclear compartments representing typical heterochromatin stably maintained during cell cycle. We explore how histone H3 variants, replicative H3.1/2 or replacement H3.3, mark these domains during the cell cycle in mouse embryonic stem cells, n...

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Main Authors: S. Arfè, T. Karagyozova, A. Forest, D. Bingham, H. Hmidan, D. Mazaud, M. Garnier, P. Le Baccon, E. Meshorer, J.-P. Quivy, G. Almouzni
Format: Article
Language:English
Published: Nature Portfolio 2025-06-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-60430-z
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